Korean Journal of Stroke 2012 ; 14 (3) : p.95~105
Focused Update of Korean Clinical Practice Guidelines for the Thrombolysis in Acute Stroke Management
(한국 뇌졸중 진료지침 급성기 치료 중 혈전용해술에 대한 내용의 부분개정)
저자 조경희1,고상배2·김대현3·박희권4·조아현5·홍근식6·유경호7·허지회8·권순억9·배희준2·오창완10·권오기10·이병철7·윤병우2·나정호4
논문 종류 Clinical Practice Guideline 전문 보기 KJS-14-95-105.pdf
Since the release of first Korean Clinical Practice Guideline of Stroke in 2009, many important new evidences have emerged in the field of thrombolytic therapy. Among the recent developments are the extended therapeutic time window of intravenous (IV) tissue plasminogen activator (tPA) up to 4.5 hours after onset, and the efforts for the wider application of IV thrombolysis to patients with minor stroke and elderly patients over 80 years old. Debates about the optimal dose of IV tPA according to the ethnic population is still ongoing. Further evidences for the efficacy of intra-arterial thrombolysis have also accumulated, including the application of various novel mechanical devices with promising results. Thus update of guideline became necessary and we revise the acute stroke management guideline, focusing on the thrombolytic therapy. (Korean J Stroke 2012;14:95-105)

KEY WORDS: Clinical practice guideline, Ischemic stroke, Acute treatment, Thrombolysis, Intravenous, Intra-arterial,
Mechanical, Recanalization